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Best Science of Aging 2025

Landrum Letter #2: The 12 Hallmarks of Aging: What the 2023 Cell Paper Means for You

Thanks to breakthroughs in longevity science, we now have a clearer picture than ever before of why we age—and more importantly, what we can do about it.

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Dr Landrum treating patient with Neurostar TMS machine
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Landrum Letter #1: Exploring a Better Way to Treat Depression: Transcranial Magnetic Stimulation (TMS)

21 million adults in the US experienced at least 1 major depressive episode in 2020. Luckily, there’s an option called Transcranial Magnetic Stimulation (TMS) that is...
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person holding back

What is Cluneal Nerve Entrapment and its Treatments?

The condition known as cluneal nerve entrapment can often be difficult to diagnose. As a result, many people who suffer from lower back or upper buttocks pain have...
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woman curled up on couch from chronic depression

How Chronic Pain and Depression Are More Connected Than You Think

Did you know that chronic pain and depression are more connected than you realize, with one increasing the chances of the other. 

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back pain being highlighted

Vertebrogenic Pain: Can I Get Rid of My Lower Back Pain?

Millions of people in the US live with chronic lower back pain, making it hard to enjoy life. Most treatments don’t achieve long-term effect. If you are experiencing...
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sad man looking out window

TMS vs ECT: Key Differences in Treating Depression

There are alternative depression treatments available such as TMS and ECT treatments. When it comes to TMS vs ECT, what are the key differences when treating...
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person holding leg

Rest Pain or Something Else? Signs of Peripheral Artery Disease

While just simply walking, you might experience leg pain or fatigue. Seems normal, doesn’t it? Maybe it’s just a sign of aging, right? Those could be signs of...
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person taking asprin

Is Aspirin an NSAID?

Aspirin is one of the most common over-the-counter drugs used. NSAIDs are not suitable for everyone and can sometimes lead to serious side effects. So, this begs the...
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woman lying on bed
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Pain Insomnia Depression Syndrome: How Pain and Sleep Connect

It has been shown that pain and sleep are connected. Pain and sleep are also linked with depression which is considered in the Pain Insomnia Depression Syndrome

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woman holding back at desk

What is Adjacent Segment Disease and How Does it Occur?

Spinal fusions can present many challenges for patients, including potentially developing Adjacent Segment Disease (ASD). Let’s take a look at how this troubling...
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Cutting Edge Health : Orlando Landrum MD

Cutting Edge Health : Orlando Landrum MD
😴 **Tired of being tired?** If you’re waking up groggy, dragging through the day, or getting elbowed for snoring like a freight train 🚂—this one’s for you. In this video, **Dr. Orlando Landrum** breaks down how **Empower Sleep** is shaking up the world of sleep health with fast, at-home testing that actually makes sense. 🌙 Sleep isn’t just downtime—it’s **prime time** for your brain, heart, and energy levels. Dr. Landrum shows how Empower Sleep helps you figure out exactly what’s messing with your nights—without needing a hospital stay or clunky machines. Just smart, simple tech that gets results. 🛌📊 💡 You’ll discover how poor sleep can quietly drain your focus, stress your heart, and mess with your mood—and how Empower Sleep helps you turn it all around. When you understand what your body’s doing at night, **you can wake up ready to go**. 🧠⚡ 👨‍⚕️ With a background in interventional neurosciences, interventional pain and anesthesiology, Dr. Landrum knows how sleep ties into your total health. He’s not just throwing facts—he’s giving you tools to **take control** of your sleep and your life. No fluff, just real solutions. 🙌💥 🛎️ So if you’re ready to stop guessing and start sleeping better, hit play now! Drop your questions in the comments and subscribe for more straight-shooting health tips from **Dr. Orlando Landrum**. #EmpowerSleep #BetterSleep #DrOrlandoLandrum #SleepTestAtHome #SleepSmarterLiveBetter 🔔 If you want to understand how to use science and modern treatments for improved mental and physical health. And/Or how to use interventional neuroscience to help you live longer and better subscribe to our channel. Subscribe @ https://www.youtube.com/@thecuttingedgehealth Practice Website: https://thecuttingedgehealth.com/ HOW TO REACH US: Ask Questions or Schedule a Virtual Appointment : info@thecuttingedgehealth.com To Schedule a Prospective appointment: Call us: (574) 766- HEAL (4325) Medical Disclaimer: All content in this video and description including: infor­ma­tion, opinions, con­tent, ref­er­ences and links is for infor­ma­tional pur­poses only. The Author does not pro­vide any med­ical advice on the Site. Access­ing, viewing, read­ing or oth­er­wise using this content does NOT cre­ate a physician-patient rela­tion­ship between you and it’s author. Pro­vid­ing per­sonal or med­ical infor­ma­tion to the Principal author does not cre­ate a physician-patient rela­tion­ship between you and the Principal author or authors. Noth­ing con­tained in this video or it’s description is intended to estab­lish a physician-patient rela­tion­ship, to replace the ser­vices of a trained physi­cian or health care pro­fes­sional, or oth­er­wise to be a sub­sti­tute for pro­fes­sional med­ical advice, diag­no­sis, or treatment. You should con­sult a licensed physi­cian.
Empower Sleep : New Sleep Technology For Better Sleep And Health
**Aging isn’t what it used to be.** In this video, we dive into the *2023 Cell* paper that redefined the **12 Hallmarks of Aging**—a science-backed blueprint of what’s really going on at the cellular level as we get older. The best part? Understanding these hallmarks gives us real power. Power to slow them down. Power to fight back. Power to age better, not just longer. This isn’t hype—it’s hard science made simple. From mitochondrial breakdown to chronic low-grade inflammation (aka "inflammaging") and DNA damage, we’re breaking down the biological culprits behind fatigue, brain fog, joint pain, and more. And most importantly, we highlight what current research suggests you can *actually* do about it. This channel is built for those who want to stay sharp, strong, and in control—regardless of what the calendar says. Whether you’re looking to stay active, feel energized, or just make sense of what your body is doing as the years roll by, you’re in the right place. Tap **Subscribe** if you're ready to outsmart aging. We post new videos weekly that translate the latest longevity science into real-world strategies. No fluff, no fads—just cutting-edge insights you can use to live better, every day. 📌 **Watch to the end** for actionable takeaways based on the most recent aging research—and drop a comment to share which hallmark felt most familiar. Let’s turn back the biological clock, one smart move at a time. 🔔 If you want to understand how to use science and modern treatments for improved mental and physical health. And/Or how to use interventional neuroscience to help you live longer and better subscribe to our channel. Subscribe @ https://www.youtube.com/@thecuttingedgehealth Practice Website: https://thecuttingedgehealth.com/ HOW TO REACH US: Ask Questions or Schedule a Virtual Appointment : info@thecuttingedgehealth.com To Schedule a Prospective appointment: Call us: (574) 766- HEAL (4325) Medical Disclaimer: All content in this video and description including: infor­ma­tion, opinions, con­tent, ref­er­ences and links is for infor­ma­tional pur­poses only. The Author does not pro­vide any med­ical advice on the Site. Access­ing, viewing, read­ing or oth­er­wise using this content does NOT cre­ate a physician-patient rela­tion­ship between you and it’s author. Pro­vid­ing per­sonal or med­ical infor­ma­tion to the Principal author does not cre­ate a physician-patient rela­tion­ship between you and the Principal author or authors. Noth­ing con­tained in this video or it’s description is intended to estab­lish a physician-patient rela­tion­ship, to replace the ser­vices of a trained physi­cian or health care pro­fes­sional, or oth­er­wise to be a sub­sti­tute for pro­fes­sional med­ical advice, diag­no­sis, or treatment. You should con­sult a licensed physi­cian.
12 hallmarks of aging: How understanding this can help you live better
🚀 **Unlock Your Potential with NAD+ Therapy!** 💡✨ Imagine waking up with boundless energy, sharper focus, and a body that feels rejuvenated from the inside out. At **Cutting Edge Health Clinic**, Dr. Orlando Landrum brings you the **latest breakthrough in cellular health—NAD+ Therapy!** 🧬⚡ 🔬 **What is NAD+?** NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every cell, responsible for energy production, DNA repair, and overall wellness. But as we age, NAD+ levels decline—leading to fatigue, brain fog, and the effects of aging. **Replenishing NAD+ can help restore vitality, enhance cognition, and promote longevity!** ⏳🧠 🔥 **Why Choose NAD+ Therapy at Cutting Edge Health?** ✔ **Boost Energy Levels** – Say goodbye to exhaustion and hello to natural, sustained energy! ⚡💪 ✔ **Sharpen Mental Clarity** – Enhance memory, focus, and mental resilience. 🧠💡 ✔ **Support Healthy Aging** – Promote cellular repair and longevity for a youthful you! ✨🕰️ ✔ **Reduce Stress & Anxiety** – NAD+ supports neurotransmitters that regulate mood and emotional balance. 🧘‍♂️😌 ✔ **Faster Recovery** – Whether it’s from burnout, illness, or intense training, NAD+ speeds up healing. 💥🏃‍♂️ 💉 **How is NAD+ Therapy Administered?** The most effective way? **IV infusions at Cutting Edge Health**, ensuring maximum absorption and benefits. Oral supplements exist, but IV therapy delivers **faster, more powerful results** so you can feel the difference quickly! 🚀💉 ✨ **Are You Ready to Take Control of Your Health?** ✨ Don’t wait to experience **the cutting-edge benefits of NAD+ Therapy!** Whether you're looking to **combat fatigue, enhance performance, or age gracefully,** we've got you covered. Contact us today! 📞 Call **(574) 766-HEAL** (4325) 🌍 Visit **[https://thecuttingedgehealth.com/](https://thecuttingedgehealth.com/)** ▶ Subscribe for more health breakthroughs: **[https://www.youtube.com/@thecuttingedgehealth](https://www.youtube.com/@thecuttingedgehealth)** #NADTherapy #BoostYourEnergy #BrainHealth #Longevity #CuttingEdgeHealth #DrOrlandoLandrum #AntiAging #Mitochondria #Biohacking #CellularHealth 🔔 If you want to understand how to use science and modern treatments for improved mental and physical health. And/Or how to use interventional neuroscience to help you live longer and better subscribe to our channel. Subscribe @ https://www.youtube.com/@thecuttingedgehealth Practice Website: https://thecuttingedgehealth.com/ HOW TO REACH US: Ask Questions or Schedule a Virtual Appointment : info@thecuttingedgehealth.com To Schedule a Prospective appointment: Call us: (574) 766- HEAL (4325) Medical Disclaimer: All content in this video and description including: infor­ma­tion, opinions, con­tent, ref­er­ences and links is for infor­ma­tional pur­poses only. The Author does not pro­vide any med­ical advice on the Site. Access­ing, viewing, read­ing or oth­er­wise using this content does NOT cre­ate a physician-patient rela­tion­ship between you and it’s author. Pro­vid­ing per­sonal or med­ical infor­ma­tion to the Principal author does not cre­ate a physician-patient rela­tion­ship between you and the Principal author or authors. Noth­ing con­tained in this video or it’s description is intended to estab­lish a physician-patient rela­tion­ship, to replace the ser­vices of a trained physi­cian or health care pro­fes­sional, or oth­er­wise to be a sub­sti­tute for pro­fes­sional med­ical advice, diag­no­sis, or treatment. You should con­sult a licensed physi­cian.
NAD+ :  A Superior Treatment For Fixing Your Mood, Fatigue And Immune System
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Client Testimonials

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Dr. Landrum and his staff are wonderful - very kind, compassionate, and they really care! Dr. Landrum really listens to his patients, asks questions, allows you to ask questions, and is very thorough. He also comes up with different options to help alleviate pain, and then makes in-depth videos to watch as well as newsletters, just to help people learn about different medical issues, and what the latest treatment options are. I cannot say enough good things about Cutting Edge Health and the care I receive.
Billie C.
Dr. Landrum and his staff are wonderful - very kind, compassionate, and they really care! Dr. Landrum really listens to his patients, asks questions, allows you to ask questions, and is very thorough. He also comes up with different options to help alleviate pain, and then makes in-depth videos to watch as well as newsletters, just to help people learn about different medical issues, and what the latest treatment options are. I cannot say enough good things about Cutting Edge Health and the care I receive.
Billie C.
I read up on a lot of reviews of Dr. Landrum before my first appointment and they have all proven to be accurate. Dr. Landrum doesn’t talk down to me like other doctors have in the past. He listens and really knows his stuff. He takes his time to make sure all your questions are answered and acts as your partner in figuring out how to address your pain. He also uses apps and the latest tech to communicate with patients and to keep track of what you’re experiencing, which I love. (I’m a tech nerd) He is also extremely kind and is quick to respond when you have questions. The name of the practice sums it up quite well. The staff is extremely pleasant and helpful, too. His office is always super clean and comfortable, especially the nice chairs in the exam rooms. I highly recommended him, and I wish my other doctors were half as good as he is.
Heather D.
I read up on a lot of reviews of Dr. Landrum before my first appointment and they have all proven to be accurate. Dr. Landrum doesn’t talk down to me like other doctors have in the past. He listens and really knows his stuff. He takes his time to make sure all your questions are answered and acts as your partner in figuring out how to address your pain. He also uses apps and the latest tech to communicate with patients and to keep track of what you’re experiencing, which I love. (I’m a tech nerd) He is also extremely kind and is quick to respond when you have questions. The name of the practice sums it up quite well. The staff is extremely pleasant and helpful, too. His office is always super clean and comfortable, especially the nice chairs in the exam rooms. I highly recommended him, and I wish my other doctors were half as good as he is.
Heather D.
Dr. Landrum has been great to work with me through my knee pain. He does virtual follow up visits, so I don't always have to travel so far. He listens carefully and gives the shots in locations that will help the most. The Cutting Edge staff are very good at keeping me notified and are readily available for any of my questions. I am very happy with Cutting Edge Health and Dr. Landrum.
Penny Whaley
Dr. Landrum has been great to work with me through my knee pain. He does virtual follow up visits, so I don't always have to travel so far. He listens carefully and gives the shots in locations that will help the most. The Cutting Edge staff are very good at keeping me notified and are readily available for any of my questions. I am very happy with Cutting Edge Health and Dr. Landrum.
Penny Whaley
Dr. Landrum and his entire staff are caring and compassionate. They listen to their patients and offer the best possible solutions to help manage your pain. Highly recommended.
Heather Leffew
Dr. Landrum and his entire staff are caring and compassionate. They listen to their patients and offer the best possible solutions to help manage your pain. Highly recommended.
Heather Leffew
Dr. Landrum has been my doctor for over 5 years now. He is truly one of the best doctors I have ever been too, he is professional, very efficient, personable and genuinely cares about his patients.
Brenda Felder
Dr. Landrum has been my doctor for over 5 years now. He is truly one of the best doctors I have ever been too, he is professional, very efficient, personable and genuinely cares about his patients.
Brenda Felder
Dr. Landrum is a very concerned and knowledgeable doctor. The staff are professional and caring people and make me feel appreciated.
Duane Cessna
Dr. Landrum is a very concerned and knowledgeable doctor. The staff are professional and caring people and make me feel appreciated.
Duane Cessna
Dr. Landrum and his staff are the best! They are all very caring, kind, and try their best to do what is best for you. This is a doctor and staff that you can fully trust with whatever your life throws at you.
Joan Hickey
Dr. Landrum and his staff are the best! They are all very caring, kind, and try their best to do what is best for you. This is a doctor and staff that you can fully trust with whatever your life throws at you.
Joan Hickey

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